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Human 6-phosphofructokinase, muscle type (PFKM) ELISA Kit

Human 6-phosphofructokinase, muscle type (PFKM) ELISA Kit

Cat no: KTE61243

Supplier: Abbkine Scientific Co.Ltd.
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Phosphofructokinase-1 (PFK-1) is the most important regulatory enzyme (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits and controlled by several activators and inhibitors. PFK-1 catalyzes one of the important "committed" steps of glycolysis, the conversion of fructose 6-phosphate and ATP to fructose 1,6-bisphosphate and ADP. PFK1 is allosterically inhibited by ATP and citrate (from the citric acid cycle) and its product. It is also inhibited by low pH to prevent the accumulation of hydrogen ions in muscle. The enzyme has two sites with different affinities for ATP which is both a substrate and an inhibitor.PFK1 is allosterically activated by a high concentration of AMP, but the most potent activator is fructose 2,6-bisphosphate, which is also produced from fructose-6-phosphate by PFK2.
Catalogue number: KTE61243
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P08237
Gene: 5213
Additional info: Human 6-phosphofructokinase, muscle type (PFKM) ELISA Kit has high sensitivity and excellent specificity for detection of Human PFKM. No significant cross-reactivity or interference between Human PFKM and analogues was observed.

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