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Human A Disintegrin And Metalloprotease 10,ADAM10 ELISA Kit

Cat no: KTE60909

Human A Disintegrin And Metalloprotease 10,ADAM10 ELISA Kit

A Disintegrin And Metalloprotease 10 is a ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. ADAM10 is a sheddase, and has a broad specificity for peptide hydrolysis reactions. New data on the ADAM10 shedding of ephrin/eph complex associated with Eph on one cell surface has determined that ADAM10 cleaves ephrin, within the ephrin/eph complex, formed between two cell surfaces. When ephrin is freed from the opposing cell, the entire ephrin/eph complex is endocytosed. This shedding in trans had not been previously shown, but may well be involved in other shedding events.

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SPECIFICATIONS

Catalog Number

KTE60909

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

102

Accession

O14672

Additional Info

Human A Disintegrin And Metalloprotease 10,ADAM10 ELISA Kit has high sensitivity and excellent specificity for detection of Human ADAM10. No significant cross-reactivity or interference between Human ADAM10 and analogues was observed.

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