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Human Abl interactor 1 (ABI1) ELISA Kit

Human Abl interactor 1 (ABI1) ELISA Kit

Cat no: KTE60868

Supplier: Abbkine Scientific Co.Ltd.
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ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling. Abi1 is adoptor protein. It interacts with c-Abl and WAVE2 which is actin polymerization regulator. It is known that Abi1 enhances the phosphorylation of WAVE2 by c-Abl. The phosphorylation of c-Abl promotes actin polymerization.Furthermore, Abi1 is component of WAVE complex. Some research paper showed that knock down of Abi1 by si(short interffering)RNA promoted degradation of WAVE complex proteins.
Catalogue number: KTE60868
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q8IZP0
Gene: 10006
Additional info: Human Abl interactor 1 (ABI1) ELISA Kit has high sensitivity and excellent specificity for detection of Human ABI1. No significant cross-reactivity or interference between Human ABI1 and analogues was observed.

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