Human Acetyl-CoA carboxylase 1 (ACACA) ELISA Kit

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT). ACC is a multi-subunit enzyme in most prokaryotes and in the chloroplasts of most plants and algae, whereas it is a large, multi-domain enzyme in the endoplasmic reticulum of most eukaryotes. The most important function of ACC is to provide the malonyl-CoA substrate for the biosynthesis of fatty acids. The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification. The human genome contains the genes for two different ACCs - ACACA and ACACB. In muscle cells, malonyl-CoA inhibits beta-oxidation.

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SPECIFICATIONS

Catalog Number

KTE60871

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

31

Accession

Q13085

Additional Info

Human Acetyl-CoA carboxylase 1 (ACACA) ELISA Kit has high sensitivity and excellent specificity for detection of Human ACACA. No significant cross-reactivity or interference between Human ACACA and analogues was observed.