Human ADAM metallopeptidase with thrombospondin type 1 motif4 (ADAMTS4) ELISA Kit

Cat no: KTE60920

Supplier: Abbkine Scientific Co.Ltd.

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ADAMTS4 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

Catalogue number:	KTE60920
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	O75173
Gene:	9507
Additional info:	Human ADAM metallopeptidase with thrombospondin type 1 motif4 (ADAMTS4) ELISA Kit has high sensitivity and excellent specificity for detection of Human ADAMTS4. No significant cross-reactivity or interference between Human ADAMTS4 and analogues was observed.

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Human ADAM metallopeptidase with thrombospondin type 1 motif4 (ADAMTS4) ELISA Kit

Cat no: KTE60920

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