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Human AF4/FMR2 family member 1 (AFF1) ELISA Kit

Human AF4/FMR2 family member 1 (AFF1) ELISA Kit

Cat no: KTE60954

Supplier: Abbkine Scientific Co.Ltd.
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The sequence of the complete open reading frame for this fusion transcript revealed that the MLL protein is homologous with DNA methyltransferase, the Drosophila trithorax gene product, and the 'AT-hook' motif of high mobility group proteins. An alternative splice that deletes the AT-hook region of MLL was identified. AF4 is a serine- and proline-rich putative transcription factor with a glutamine-rich carboxyl terminus. The composition of the complete MLL-AF4 fusion product argues that it may act through either a gain-of-function or a dominant-negative mechanism in leukemogenesis. This gene is also symbolized MLLT2
Catalogue number: KTE60954
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P51825
Gene: 4299
Additional info: Human AF4/FMR2 family member 1 (AFF1) ELISA Kit has high sensitivity and excellent specificity for detection of Human AFF1. No significant cross-reactivity or interference between Human AFF1 and analogues was observed.

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