Human Aldo-keto reductase family 1 member B10 (AKR1B10) ELISA Kit

Cat no: KTE60639

Supplier: Abbkine Scientific Co.Ltd.

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Aldose reductase (AR) is an NADPH-dependent enzyme that was first identified by its ability to reduce glucose to sorbitol. The deduced 316-amino acid AKR1B10 protein shares 71% amino acid identity with AR. Northern blot analysis revealed that AKR1B10 is overexpressed in 54% of HCCs, while AR is overexpressed in 29% of HCCs. Northern blot analysis of normal tissues showed that unlike the ubiquitously expressed AR, AKR1B10 is expressed most abundantly in small intestine and colon, with lower levels in liver, thymus, prostate, testis, and skeletal muscle. AR and ARL1 reduce a similar spectrum of aromatic and aliphatic aldehyde substrates.Highest expression of AKR1B10 in adrenal gland, with modest expression in stomach, placenta, small intestine, and pancreas, and lower expression in all other tissues tested.

Catalogue number:	KTE60639
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	O60218
Gene:	57016
Additional info:	Human Aldo-keto reductase family 1 member B10 (AKR1B10) ELISA Kit has high sensitivity and excellent specificity for detection of Human AKR1B10. No significant cross-reactivity or interference between Human AKR1B10 and analogues was observed.

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Human Aldo-keto reductase family 1 member B10 (AKR1B10) ELISA Kit

Cat no: KTE60639

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