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Human Aldose Reductase (AR) ELISA Kit

Human Aldose Reductase (AR) ELISA Kit

Cat no: KTE60638

Supplier: Abbkine Scientific Co.Ltd.
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The androgen receptor (AR) is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS).
Catalogue number: KTE60638
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P15121
Gene: 231
Additional info: Human Aldose Reductase (AR) ELISA Kit has high sensitivity and excellent specificity for detection of Human AKR1B1. No significant cross-reactivity or interference between Human AKR1B1 and analogues was observed.

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