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Human Alpha-2C adrenergic receptor (ADRA2C) ELISA Kit

Cat no: KTE60948

Human Alpha-2C adrenergic receptor (ADRA2C) ELISA Kit

Alpha-2-adrenergic receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity.ADRa2C encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

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SPECIFICATIONS

Catalog Number

KTE60948

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

152

Accession

P18825

Additional Info

Human Alpha-2C adrenergic receptor (ADRA2C) ELISA Kit has high sensitivity and excellent specificity for detection of Human ADRA2C. No significant cross-reactivity or interference between Human ADRA2C and analogues was observed.

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