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Human Alpha-actinin-4 (ACTN-4) ELISA Kit

Cat no: KTE60901


Supplier: Abbkine Scientific Co.Ltd.
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Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Alpha-actinin-4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Catalogue number: KTE60901
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O43707
Gene: 81
Additional info: Human Alpha-actinin-4 (ACTN-4) ELISA Kit has high sensitivity and excellent specificity for detection of Human ACTN4. No significant cross-reactivity or interference between Human ACTN4 and analogues was observed.

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