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Human Amiloride-sensitive sodium channel subunit alpha (SCNN1A) ELISA Kit

Human Amiloride-sensitive sodium channel subunit alpha (SCNN1A) ELISA Kit

Cat no: KTE60737

Supplier: Abbkine Scientific Co.Ltd.
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Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. Amiloride Sensitive Sodium Channel Subunit Alpha is the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Highly expressed in kidney and lung. Detected at intermediate levels in pancreas and liver, and at low levels in heart and placenta. Isoform 1 and isoform 2 predominate in all tissues. Expression of isoform 3, isoform 4 and isoform 5 is very low or not detectable, except in lung and heart.
Catalogue number: KTE60737
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P37088
Gene: 6337
Additional info: Human Amiloride-sensitive sodium channel subunit alpha (SCNN1A) ELISA Kit has high sensitivity and excellent specificity for detection of Human SCNN1A. No significant cross-reactivity or interference between Human SCNN1A and analogues was observed.

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