Human Angiotensin converting enzyme 2 (ACE2) ELISA Kit

ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin ,or the conversion of angiotensin II to angiotensin. ACE 2 has direct effects on cardiac function, and is expressed predominantly in vascular endothelial cells of the heart and the kidneys.By EST database searching for sequences showing homology to the zinc metalloprotease angiotensin-I converting enzyme (ACE) and by screening a human lymphoma cDNA library, Tipnis et al. (2000) cloned a full-length ACE2 cDNA, which they called ACEH, encoding a deduced 805-amino acid protein that shares approximately 40% identity with the N- and C-terminal domains of ACE. ACE2 contains a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor.

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SPECIFICATIONS

Catalog Number

KTE60876

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

59272

Accession

Q9BYF1

Additional Info

Human Angiotensin converting enzyme 2 (ACE2) ELISA Kit has high sensitivity and excellent specificity for detection of Human ACE2. No significant cross-reactivity or interference between Human ACE2 and analogues was observed.