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Human Apoptosis inducing factor (AIF) ELISA Kit

Cat no: KTE60633

Human Apoptosis inducing factor (AIF) ELISA Kit

Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing DNA fragmentation and chromatin condensation. It also acts as an NADH oxidase. Another AIF function is to regulate the permeability of the mitochondrial membrane upon apoptosis.\nNormally it is found behind the outer membrane of the mitochondria and is therefore secluded from the nucleus. However, when the mitochondria is damaged, it moves to the cytosol and to the nucleus.\nInactivation of AIF leads to resistance of embryonic stem cells to death following the withdrawal of growth factors indicating that it is involved in apoptosis.

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SPECIFICATIONS

Catalog Number

KTE60633

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

9131

Accession

O95831

Additional Info

Human Apoptosis inducing factor (AIF) ELISA Kit has high sensitivity and excellent specificity for detection of Human AIFM1. No significant cross-reactivity or interference between Human AIFM1 and analogues was observed.

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