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Human Autoimmune regulator (AIRE) ELISA Kit

Human Autoimmune regulator (AIRE) ELISA Kit

Cat no: KTE60636

Supplier: Abbkine Scientific Co.Ltd.
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The Autoimmune Regulator is expressed in the thymus. It causes transcription of a wide selection of organ-specific genes. This reduces the threat of autoimmunity occurring by allowing the elimination of autoreactive T cells by the process of negative selection if they are too reactive to self. It is mutated in the rare autoimmune syndrome Autoimmune Polyendocrinopathy Syndrome type 1 (APS-1), also known as Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED). Disruption of AIRE results in the development of a range of autoimmune diseases, the most common clinical conditions in the syndrome are hypoparathyroidism, primary adrenocortical failure and chronic mucocutaneous candidiasis. AIRE is expressed primarily in the thymus
Catalogue number: KTE60636
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O43918
Gene: 326
Additional info: Human Autoimmune regulator (AIRE) ELISA Kit has high sensitivity and excellent specificity for detection of Human AIRE. No significant cross-reactivity or interference between Human AIRE and analogues was observed.

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