Human Basic salivary proline-rich protein 3 (PRB3) ELISA Kit

Basic salivary proline-rich protein 3 is a proline-rich salivary protein. It is a major constituent of parotid saliva. This protein is proposed to act as a bacterial receptor. This gene and five other genes that also encode salivary proline-rich proteins (PRPs), as well as a gene encoding a lacrimal gland PRP, form a PRP gene cluster in the chromosomal 12p13 region.The G1-8 protein variant was found in Ashkenazi Jews with a gene frequency of approximately 0.008 but was not found in the general Caucasian, black, or Japanese populations. Both G1-8, coded by the PRB3 locus, and Pa-1, coded by the PRH1 locus, are disulfide bonded and probably modify salivary peroxidase (part of an important intraoral antibacterial system) through formation of disulfide-bonded heterodimers.

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SPECIFICATIONS

Catalog Number

KTE61187

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Accession

Q04118

Additional Info

Human Basic salivary proline-rich protein 3 (PRB3) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRB3. No significant cross-reactivity or interference between Human PRB3 and analogues was observed.