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Human Bence-Jones protein (BJP) ELISA Kit

Cat no: KTE62574

Human Bence-Jones protein (BJP) ELISA Kit

A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa. Detection of Bence Jones protein may be suggestive of multiple myeloma or WaldenstrГ¶m's macroglobulinemia.Bence Jones proteins are particularly diagnostic of multiple myeloma in the context of end-organ manifestations such as renal failure, lytic (or "punched out") bone lesions, anemia, or large numbers of plasma cells in the bone marrow of patients. Bence Jones proteins are present in 2/3 of multiple myeloma cases. The proteins are immunoglobulin light chains (paraproteins) and are produced by neoplastic plasma cells. They can be kappa (most of the time) or lambda. The light chains can be immunoglobulin fragments or single homogeneous immunoglobulins.

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SPECIFICATIONS

Catalog Number

KTE62574

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human Bence-Jones protein (BJP) ELISA Kit has high sensitivity and excellent specificity for detection of Human BJP. No significant cross-reactivity or interference between Human BJP and analogues was observed.

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