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Human Bridging integrator 2 (BIN2) ELISA Kit

Human Bridging integrator 2 (BIN2) ELISA Kit

Cat no: KTE62436

Supplier: Abbkine Scientific Co.Ltd.
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BIN2 has acidic and serine/proline-rich stretches but lacks a C-terminal SH3 domain or a MYC-interacting region. Northern blot analysis revealed expression of a major 2.6-kb transcript that was highest in spleen and peripheral blood leukocytes and also high in thymus, colon, and placenta, suggesting preferential expression in hematopoietic tissues. Strong expression was detected in lymphoid and granulocytic cell lines but not other cell lines. Coimmunoprecipitation and Western blot analyses showed expression of an 80-kD protein that interacts with the N-terminal portion of the BAR domain of BIN1 isoforms but not with AMPH. Immunofluorescence microscopy demonstrated cytosolic expression and lack of receptor-mediated endocytic function for BIN2. Functional analysis showed that BIN2 lacks tumor suppressor features.
Catalogue number: KTE62436
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q9UBW5
Gene: 51411
Additional info: Human Bridging integrator 2 (BIN2) ELISA Kit has high sensitivity and excellent specificity for detection of Human BIN2. No significant cross-reactivity or interference between Human BIN2 and analogues was observed.

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