Human CAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) ELISA Kit

Cat no: KTE61152

Supplier: Abbkine Scientific Co.Ltd.

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cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase A (PKA), which transduces the signal through phosphorylation of different target proteins. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. TSE1 is one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Functional mutations in this gene cause Carney complex (CNC), an autosomal dominant multiple neoplasia syndrome. This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2.

Catalogue number:	KTE61152
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	P10644
Gene:	5573
Additional info:	Human CAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) ELISA Kit has high sensitivity and excellent specificity for detection of Human PRKAR1A. No significant cross-reactivity or interference between Human PRKAR1A and analogues was observed.

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Human CAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) ELISA Kit

Cat no: KTE61152

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