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Human Caspase-14 (CASP14) ELISA Kit

Cat no: KTE62430

Human Caspase-14 (CASP14) ELISA Kit

Caspase-14 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

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SPECIFICATIONS

Catalog Number

KTE62430

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

23581

Accession

P31944

Additional Info

Human Caspase-14 (CASP14) ELISA Kit has high sensitivity and excellent specificity for detection of Human CASP14. No significant cross-reactivity or interference between Human CASP14 and analogues was observed.

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