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Human Caspase-3 (CASP3) ELISA Kit

Human Caspase-3 (CASP3) ELISA Kit

Cat no: KTE62614

Supplier: Abbkine Scientific Co.Ltd.
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Caspase-3 (CPP-32, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position (2).a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.
Catalogue number: KTE62614
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P42574
Gene: 836
Additional info: Human Caspase-3 (CASP3) ELISA Kit has high sensitivity and excellent specificity for detection of Human CASP3. No significant cross-reactivity or interference between Human CASP3 and analogues was observed.

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