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Human Centromere Protein(CENP-B) ELISA Kit

Human Centromere Protein(CENP-B) ELISA Kit

Cat no: KTE62684

Supplier: Abbkine Scientific Co.Ltd.
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Centromere Protein B is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA.This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
Catalogue number: KTE62684
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P07199
Gene: 1059
Additional info: Human Centromere Protein(CENP-B) ELISA Kit has high sensitivity and excellent specificity for detection of Human CENPB. No significant cross-reactivity or interference between Human CENPB and analogues was observed.

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