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Human Complement fragment 4a (C4a) ELISA Kit

Human Complement fragment 4a (C4a) ELISA Kit

Cat no: KTE62616

Supplier: Abbkine Scientific Co.Ltd.
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Complement C4-A is the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
Catalogue number: KTE62616
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P0C0L4
Gene: 720
Additional info: Human Complement fragment 4a (C4a) ELISA Kit has high sensitivity and excellent specificity for detection of Human C4A. No significant cross-reactivity or interference between Human C4A and analogues was observed.

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