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Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A) ELISA Kit

Cat no: KTE62548

Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A) ELISA Kit

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation.В DNMT3AВ encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.The mouse genes, termed Dnmt3a and Dnmt3b, show little sequence similarity to mouse Dnmt1 and Dnmt2, and masc1 from Ascobolus. The Dnmt3a cDNA encodes a protein of 908 amino acids. The human DNMT3A and DNMT3B cDNAs are highly homologous to the mouse genes. Dnmt3a and Dnmt3b transcripts were abundantly expressed in undifferentiated embryonic stem cells.

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SPECIFICATIONS

Catalog Number

KTE62548

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1788

Accession

Q9Y6K1

Additional Info

Human DNA (cytosine-5)-methyltransferase 3A (DNMT3A) ELISA Kit has high sensitivity and excellent specificity for detection of Human DNMT3A. No significant cross-reactivity or interference between Human DNMT3A and analogues was observed.

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SUPPLIER INFO

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