Human DNA-directed RNA polymerase I subunit RPA12 (ZNRD1) ELISA Kit

ZNRD1 encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined.Lepourcelet et al. (1996) identified ZNRD1, which they called HTEX6, as 1 of several genes in the HLA-A /HLA-F region of chromosome 6. The deduced protein contains 2 potential zinc-binding motifs and shows significant homology with the A12.2 subunit of yeast polymerase I and mouse Tctex6. Coriton et al. (2000) cloned ZNRD1 from a testis cDNA library. The deduced protein contains 126 amino acids. They also identified splice variants predicted to encode shorter peptides.

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SPECIFICATIONS

Catalog Number

KTE62446

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

30834

Accession

Q9P1U0

Additional Info

Human DNA-directed RNA polymerase I subunit RPA12 (ZNRD1) ELISA Kit has high sensitivity and excellent specificity for detection of Human ZNRD1. No significant cross-reactivity or interference between Human ZNRD1 and analogues was observed.