Human E3 ubiquitin-protein ligase TRIM68 (TRIM68) ELISA Kit

TRIM68В contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.The deduced 485-amino acid protein has a calculated molecular mass of 56 kD. It has a RING finger domain, followed by a B box and a coiled-coil region. The deduced protein contains an N-terminal cys-his cluster, followed by a bipartite nuclear localization signal, a coiled-coil leucine zipper-like domain, and a C-terminal RET finger protein (TRIM27)-like domain.

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SPECIFICATIONS

Catalog Number

KTE62549

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

55128

Accession

Q6AZZ1

Additional Info

Human E3 ubiquitin-protein ligase TRIM68 (TRIM68) ELISA Kit has high sensitivity and excellent specificity for detection of Human TRIM68. No significant cross-reactivity or interference between Human TRIM68 and analogues was observed.