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Human E3 ubiquitin-protein ligase UBR4 (UBR4) ELISA Kit

Human E3 ubiquitin-protein ligase UBR4 (UBR4) ELISA Kit

Cat no: KTE60094

Supplier: Abbkine Scientific Co.Ltd.
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RBAF600 associates with RB in the nucleus and with Ca(2+)-bound calmodulin in the cytoplasm.p600 and RB appears to act as a chromatin scaffold, and in the cytoplasm p600 and clathrin form a meshwork structure which could contribute to cytoskeletal organization and membrane morphogenesis. Reduced expression of p600 with interfering RNA abrogated integrin-mediated ruffled membrane formation and prevented activation of integrin-mediated survival pathways. The deduced 5,183-amino acid protein has a calculated molecular mass of 573.5 kD. Immunostaining of human foreskin fibroblasts localized p600 in a continuous meshwork pattern from the nucleus to the cytoplasm, passing through the nuclear envelope. In the cytoplasm, p600 was concentrated at the leading edge of membrane structures.
Catalogue number: KTE60094
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q5T4S7
Gene: 23352
Additional info: Human E3 ubiquitin-protein ligase UBR4 (UBR4) ELISA Kit has high sensitivity and excellent specificity for detection of Human UBR4. No significant cross-reactivity or interference between Human UBR4 and analogues was observed.

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