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Human Elafin (PI3) ELISA Kit

Cat no: KTE61218

Human Elafin (PI3) ELISA Kit

Elafin is an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Chang et al. and Schalkwijk et al. described a low molecular weight elastase inhibitor derived from psoriatic skin and termed SKALP for 'skin-derived antileukoproteinase.' They demonstrated that this inhibitor can be found in the epidermis of several inflammatory skin diseases, but not in normal human epidermis. Wiedow et al. referred to this molecule as elafin, and Sallenave and Ryle referred to it as elastase-specific inhibitor. It is found in the urine of psoriatic patients, and immunohistochemical studies showed that SKALP/elafin is found in the suprabasal differentiated keratinocytes of psoriatic epidermis. Molhuizen et al. isolated a precursor of SKALP/elafin from cultured keratinocytes and cloned its cDNA.

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SPECIFICATIONS

Catalog Number

KTE61218

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5266

Accession

P19957

Additional Info

Human Elafin (PI3) ELISA Kit has high sensitivity and excellent specificity for detection of Human PI3. No significant cross-reactivity or interference between Human PI3 and analogues was observed.

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