Human Epidermal growth factor receptor (EGFR) ELISA Kit

The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. EGFRВ exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor ? (TGF?). ErbB2 has no known direct activating ligand, and may be in an activated state constitutively or become active upon heterodimerization with other family members such as EGFR.

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SPECIFICATIONS

Catalog Number

KTE62577

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

396494

Accession

P13387

Additional Info

Human Epidermal growth factor receptor (EGFR) ELISA Kit has high sensitivity and excellent specificity for detection of Human EGFR. No significant cross-reactivity or interference between Human EGFR and analogues was observed.