Human Excitatory amino acid transporter 3 (SLC1A1) ELISA Kit

SLC1A1 encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.\nExpressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers).

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SPECIFICATIONS

Catalog Number

KTE60620

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

6505

Accession

P43005

Additional Info

Human Excitatory amino acid transporter 3 (SLC1A1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SLC1A1. No significant cross-reactivity or interference between Human SLC1A1 and analogues was observed.