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Human Exportin-1 (XPO1) ELISA Kit

Cat no: KTE60012


Supplier: Abbkine Scientific Co.Ltd.
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Exportin-1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus.
Catalogue number: KTE60012
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O14980
Gene: 7514
Additional info: Human Exportin-1 (XPO1) ELISA Kit has high sensitivity and excellent specificity for detection of Human XPO1. No significant cross-reactivity or interference between Human XPO1 and analogues was observed.

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