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Human Exportin-5 (XPO5) ELISA Kit

Human Exportin-5 (XPO5) ELISA Kit

Cat no: KTE60011

Supplier: Abbkine Scientific Co.Ltd.
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Exportin-5 belongs to a large family of karyopherins that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments. The deduced 1,205-amino acid protein has a calculated molecular mass of about 136 kD. XPO5 and XPO1 share 25% amino acid identity. Northern blot analysis detected transcripts of about 3.6 and 5.0 kb in all tissues examined.XPO5 bound the nucleoporins NUP214 and NUP153 in a RAN-GTP-independent manner and bound a cargo protein, ILF3, in a RAN-GTP-dependent manner. XPO5 bound ILF3 at its double-stranded RNA-binding domain (dsRBD) and also bound the dsRBDs of other proteins. XPO5 directly interacted with VA1 RNA in a RAN-GTP-dependent manner.
Catalogue number: KTE60011
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q9HAV4
Gene: 57510
Additional info: Human Exportin-5 (XPO5) ELISA Kit has high sensitivity and excellent specificity for detection of Human XPO5. No significant cross-reactivity or interference between Human XPO5 and analogues was observed.

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