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Human Extracellular sulfatase Sulf-1 (SULF1) ELISA Kit

Human Extracellular sulfatase Sulf-1 (SULF1) ELISA Kit

Cat no: KTE60400

Supplier: Abbkine Scientific Co.Ltd.
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Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules. The deduced 871-amino acid protein contains an N-terminal signal sequence, followed by a sulfatase domain, a hydrophilic region, and a C-terminal substrate recognition domain. It also has a coiled-coil region, 10 N-glycosylation sites, and several consensus furin cleavage sites. SULF1 shares about 64% identity with SULF2 and 93% identity with mouse Sulf1.
Catalogue number: KTE60400
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q8IWU6
Gene: 23213
Additional info: Human Extracellular sulfatase Sulf-1 (SULF1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SULF1. No significant cross-reactivity or interference between Human SULF1 and analogues was observed.

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