Human Follistatin Like Protein 1 (FSTL1) ELISA Kit

FSTL1В encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.FSTL1 encodes a deduced 308-amino acid protein with an N-terminal signal peptide of 20 amino acids. The number and distribution of the cysteine residues supports the existence of several intramolecular disulfide bridges.Immunohistochemical analysis demonstrated increased expression in Cd90 (THY1)-positive fibroblasts, particularly early in CIA. Monkey fibroblasts transfected with human FSTL1 spontaneously secreted more IL6, and human monocytes transfected with FSTL1 and stimulated with mitogens expressed higher IL1B, TNF, and IL6.

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SPECIFICATIONS

Catalog Number

KTE62635

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

11167

Accession

Q12841

Additional Info

Human Follistatin Like Protein 1 (FSTL1) ELISA Kit has high sensitivity and excellent specificity for detection of Human FSTL1. No significant cross-reactivity or interference between Human FSTL1 and analogues was observed.