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Human Fragile histidine triad (FHIT) ELISA Kit

Human Fragile histidine triad (FHIT) ELISA Kit

Cat no: KTE62589

Supplier: Abbkine Scientific Co.Ltd.
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a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas.The last 21 amino acids at the C terminus of UBC9 appear to be unimportant for its biologic activity, since a UBC9 mutant harboring a deletion of these amino acids could still restore normal growth of yeast containing a temperature-sensitive mutation in the homolog UBC9 gene. Mutational analysis indicated that UBC9 was associated with the C-terminal portion of FHIT.
Catalogue number: KTE62589
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P49789
Gene: 2272
Additional info: Human Fragile histidine triad (FHIT) ELISA Kit has high sensitivity and excellent specificity for detection of Human FHIT. No significant cross-reactivity or interference between Human FHIT and analogues was observed.

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