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Human G protein-coupled receptor 109A (GPR109A) ELISA Kit

Cat no: KTE62550

Human G protein-coupled receptor 109A (GPR109A) ELISA Kit

GPR109A is a high affinity receptor for nicotinic acid (niacin) and is a member of the nicotinic acid receptor family of G protein-coupled receptors (the other identified member being GPR109B).GPR109A is a Gi / Go protein-coupled receptor with high affinity for nicotinic acid.GPR109A is believed to be an important biomolecular target of niacin which is a widely prescribed drug for the treatment of dyslipidemia and to increase HDL cholesterol but whose therapeutic use is limited by flushing. In GPR109A knockout mice, the effects of niacin on both lipids and flushing is eliminated. Furthermore in arrestin beta 1 knockout mice, niacin's effect on flushing is greatly reduced while the lipid modifying effects are maintained.

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SPECIFICATIONS

Catalog Number

KTE62550

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human G protein-coupled receptor 109A (GPR109A) ELISA Kit has high sensitivity and excellent specificity for detection of Human GPR109A. No significant cross-reactivity or interference between Human GPR109A and analogues was observed.

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