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Human Gamma-glutamylcysteine synthetase (?-GCS) ELISA Kit

Human Gamma-glutamylcysteine synthetase (?-GCS) ELISA Kit

Cat no: KTE62527

Supplier: Abbkine Scientific Co.Ltd.
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Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.It catalyses the ATP-dependent condensation of cysteine and glutamate to form the dipeptide gamma-glutamylcysteine. The peptide bond in this peptide product is between the carboxylate group of the glutamate and the amino group of the cysteine.The product of the GCL-mediated condensation reaction of L-glutamate and L-cysteine is gamma-glutamylcysteine, which is readily condensed with glycine, by glutathione synthetase, to form glutathione.
Catalogue number: KTE62527
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Additional info: Human Gamma-glutamylcysteine synthetase (?-GCS) ELISA Kit has high sensitivity and excellent specificity for detection of Human ?-GCS. No significant cross-reactivity or interference between Human ?-GCS and analogues was observed.

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