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Human Glia-derived nexin (SERPINE2) ELISA Kit

Human Glia-derived nexin (SERPINE2) ELISA Kit

Cat no: KTE60693

Supplier: Abbkine Scientific Co.Ltd.
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Protease nexin I is a 44-kD thrombin and urokinase inhibitor released by human foreskin fibroblasts. PN-I shares several features with antithrombin III , an abundant plasma thrombin inhibitor. Both PN-I and AT-III have high affinities for heparin, and heparin accelerates their rate of thrombin inhibition. In addition, the published sequence of 28 amino acids at the N-terminus of PN-I is identical to the N-terminal amino acid sequence of a glial-derived neurite promoting factor. Two forms, designated alpha and beta, were identified. These differed only by the insertion of 3 nucleotides into the coding sequence, and apparently arose by utilization of an alternative splice acceptor site in the PN1 gene. In the resulting proteins, alpha-PN-I contains an arginine residue at position 310, whereas beta-PN-I contains threonine-lysine residues.
Catalogue number: KTE60693
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P07093
Gene: 5270
Additional info: Human Glia-derived nexin (SERPINE2) ELISA Kit has high sensitivity and excellent specificity for detection of Human SERPINE2. No significant cross-reactivity or interference between Human SERPINE2 and analogues was observed.

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