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Human Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit

Human Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit

Cat no: KTE61005

Supplier: Abbkine Scientific Co.Ltd.
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QPCT encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. The deduced 361-amino acid protein has a calculated molecular mass of about 41 kD. It contains an N-terminal signal peptide region, several glycosylation and phosphorylation sites, and 2 cysteine residues conserved between the bovine and human enzymes. QPCT shares 86% overall sequence identity with the bovine homolog.Glutaminyl cyclase expression was upregulated in the cortices of individuals with Alzheimer disease and correlated with the appearance of pE-modified amyloid beta.
Catalogue number: KTE61005
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q16769
Gene: 25797
Additional info: Human Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit has high sensitivity and excellent specificity for detection of Human QPCT. No significant cross-reactivity or interference between Human QPCT and analogues was observed.

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