Human Glycogen phosphorylase, brain form (PYGB) ELISA Kit

PYGB is a new isozyme of glycogen phosphorylase (1,4-D-glucan:orthosphosphate D-glucosyltransferase; EC 2.4.1.1) from a cDNA library prepared from a human brain astrocytoma cell line. Blot-hybridization analysis showed that the message is preferentially expressed in human brain, but is also found at a low level in human fetal liver and adult liver and muscle tissues. The protein sequence deduced from the nucleotide sequence was 862 amino acids long compared with 846 and 841 amino acids for the liver (PYGL) and muscle (PYGM) isozymes, respectively. The greater length of brain phosphorylase was found to be due entirely to an extension at the c-terminal portion of the protein. Muscle and brain isozymes shared greater similarities with each other than either did with the liver sequence.

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SPECIFICATIONS

Catalog Number

KTE61018

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

5834

Accession

P11216

Additional Info

Human Glycogen phosphorylase, brain form (PYGB) ELISA Kit has high sensitivity and excellent specificity for detection of Human PYGB. No significant cross-reactivity or interference between Human PYGB and analogues was observed.