Interleukin-1beta (IL-1beta) has a wide spectrum of inflammatory, metabolic, haemopoietic, and immunological properties (1). IL-1 beta plays a significant role in hippocampal synaptic function (2), and is a potential genetic marker as indicator of gastric cancer risk (3). High plasma level of Interleukin-1 beta (IL-1b) is associated with rheumatoid and osteoarthritic joint disease (4), infectious gastroenteritis (5), neurodegeneration (6), and breast cancer (7). High gingival crevicular fluid levels of interleukin-1beta is related to type 2 diabetes (8).