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Human Leukocyte elastase inhibitor (SERPINB1) ELISA Kit

Human Leukocyte elastase inhibitor (SERPINB1) ELISA Kit

Cat no: KTE60700

Supplier: Abbkine Scientific Co.Ltd.
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Monocyte/neutrophil elastase inhibitor (EI) is a protein of approximately 42,000 Mr with serpin-like functional properties. Remold-O'Donnell et al. (1992) cloned EI cDNA and identified 3 EI mRNA species of 1.5, 1.9, and 2.6 kb in monocyte-like cells and no hybridizing mRNA in lymphoblastoid cells lacking detectable EI enzymatic activity. The cDNA open reading frame encoded a 379-amino acid protein. Its sequence established EI as a member of the serpin superfamily. Sequence alignment indicated that the reactive center P1 residue is cys-344, consistent with abrogation of elastase inhibitory activity by iodoacetamide and making EI a naturally occurring cys-serpin. Other elastase inhibitors include alpha-1-antitrypsin (PI) and secretory leukocyte protease inhibitor (SLPI).
Catalogue number: KTE60700
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: P30740
Gene: 1992
Additional info: Human Leukocyte elastase inhibitor (SERPINB1) ELISA Kit has high sensitivity and excellent specificity for detection of Human SERPINB1. No significant cross-reactivity or interference between Human SERPINB1 and analogues was observed.

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