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Human Lysophosphatidic acid (LPA) ELISA Kit

Cat no: KTE62534

Human Lysophosphatidic acid (LPA) ELISA Kit

Lipoprotein(a) consists of an LDL-like particle and the specific apolipoprotein(a) , which is covalently bound to the apoB of the LDL like particle. Lp(a) plasma concentrations are highly heritable and mainly controlled by the apolipoprotein(a) geneВ located on chromosome 6q26-27. Apo(a) proteins vary in size due to a size polymorphism , which is caused by a variable number of so called kringle IV repeats in the LPA gene. This size variation at the gene level is expressed on the protein level as well, resulting in apo(a) proteins with 10 to > 50 kringle IV repeats . These variable apo(a) sizes are known as "apo(a) isoforms". There is a general inverse correlation between the size of the apo(a)isoform and the Lp(a) plasma concentration which is caused by a variable rate of degradation before the apo(a) protein has matured for Lp(a) assembly.

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SPECIFICATIONS

Catalog Number

KTE62534

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Additional Info

Human Lysophosphatidic acid (LPA) ELISA Kit has high sensitivity and excellent specificity for detection of Human LPA. No significant cross-reactivity or interference between Human LPA and analogues was observed.

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