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Human Meckelin (TMEM67) ELISA Kit

Human Meckelin (TMEM67) ELISA Kit

Cat no: KTE60264

Supplier: Abbkine Scientific Co.Ltd.
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TMEM67 localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). The human TMEM67 gene encodes a 995-amino acid protein, which they authors called meckelin, with a calculated unglycosylated weight of 108 kD. Human and rat meckelin share 84% identity. Meckelin was predicted to contain a signal peptide, at least 2 cysteine-rich repeats, and a 490-residue extracellular region with 4 N-linked glycosylated sites, followed by 7 transmembrane domains and a 30-residue cytoplasmic tail.
Catalogue number: KTE60264
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q5HYA8
Gene: 91147
Additional info: Human Meckelin (TMEM67) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMEM67. No significant cross-reactivity or interference between Human TMEM67 and analogues was observed.

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