Human Meiotic recombination protein SPO11 (SPO11) ELISA Kit

Cat no: KTE60333

Supplier: Abbkine Scientific Co.Ltd.

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SPO11 is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. The human and the mouse SPO11 proteins share 82% amino acid identity, but only 20 to 30% with other eukaryotic homologs such as Drosophila and C. elegans. Both the mouse and human SPO11 exons 2 and 8 are subject to alternative splicing. Northern blot analysis showed that mouse Spo11 is expressed in testis and thymus as a 1.8-kb mRNA, whereas human SPO11 is expressed in testis as a 2.0-kb transcript. RT-PCR revealed that human SPO11 is also expressed in prostate, fetal testis, thymus, and some carcinoma cell lines.

Catalogue number:	KTE60333
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q9Y5K1
Gene:	23626
Additional info:	Human Meiotic recombination protein SPO11 (SPO11) ELISA Kit has high sensitivity and excellent specificity for detection of Human SPO11. No significant cross-reactivity or interference between Human SPO11 and analogues was observed.

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Human Meiotic recombination protein SPO11 (SPO11) ELISA Kit

Cat no: KTE60333

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