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Human Membrane attack complex (MAC) ELISA Kit

Cat no: KTE62641


Supplier: Abbkine Scientific Co.Ltd.
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Protectin, a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation.This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Catalogue number: KTE62641
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Additional info: Human Membrane attack complex (MAC) ELISA Kit has high sensitivity and excellent specificity for detection of Human MAC. No significant cross-reactivity or interference between Human MAC and analogues was observed.

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