Human Mitochondrial import receptor subunit TOM22 homolog (TOMM22) ELISA Kit

The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins from the cytosol into the mitochondria. The deduced 142-amino acid human protein, which is approximately 33% similar to the yeast proteins, contains an N-terminal negatively charged region, an internal hydrophobic transmembrane region, and a C-terminal region with a glutamine-rich segment. Immunoblot analysis and fluorescence microscopy showed expression of a 21-kD mitochondrial membrane protein with its N and C termini exposed to the cytosol and intermembrane space of the mitochondrial outer membrane, respectively.An association between the rat Tomm22 protein, which is 94% identical to the human protein, and Tomm40 was observed.

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SPECIFICATIONS

Catalog Number

KTE60164

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

56993

Accession

Q9NS69

Additional Info

Human Mitochondrial import receptor subunit TOM22 homolog (TOMM22) ELISA Kit has high sensitivity and excellent specificity for detection of Human TOMM22. No significant cross-reactivity or interference between Human TOMM22 and analogues was observed.