Human Mitochondrial import receptor subunit TOM5 homolog (TOMM5) ELISA Kit

Cat no: KTE60161

Supplier: Abbkine Scientific Co.Ltd.

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The fungal preprotein translocase of the mitochondrial outer membrane (TOM complex) comprises import receptors Tom70, Tom20, and Tom22, import channel Tom40, and small Tom proteins Tom5, Tom6, and Tom7, which regulate TOM complex assembly. These components are conserved in mammals; unlike the other components, however, Tom5 and Tom6 remain unidentified in mammals. These small Tom proteins are associated with Tom40 in the TOM complex. Knockdown of Tom7, but not Tom5 and Tom6, strongly compromised stability of the TOM complex. Conversely, knockdown of hTom40 decreased the level of all small Tom proteins. Matrix import of preprotein was affected by double knockdown of any combination of small Tom proteins. These results indicate that human small Tom proteins maintain the structural integrity of the TOM complex.

Catalogue number:	KTE60161
Reactivities:	Human
Applications:	ELISA
Size:	48T, 96T, 96T5, 96T50
Accession:	Q8N4H5
Gene:	401505
Additional info:	Human Mitochondrial import receptor subunit TOM5 homolog (TOMM5) ELISA Kit has high sensitivity and excellent specificity for detection of Human TOMM5. No significant cross-reactivity or interference between Human TOMM5 and analogues was observed.

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Human Mitochondrial import receptor subunit TOM5 homolog (TOMM5) ELISA Kit

Cat no: KTE60161

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