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Human Mitochondrial import receptor subunit TOM70 (TOMM70A) ELISA Kit

Human Mitochondrial import receptor subunit TOM70 (TOMM70A) ELISA Kit

Cat no: KTE60159

Supplier: Abbkine Scientific Co.Ltd.
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The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria.TOMM70A is 29% identical to the mitochondrial precursor protein import receptor of Neurospora crassa. RT-PCR analysis detected ubiquitous expression of KIAA0719, with relatively weak expression in pancreas, testis, and spleen.the cytosolic chaperones HSP90 and HSP70 dock onto a specialized tetratricopeptide domain in the import receptor TOMM70 at the outer mitochondrial membrane. This interaction served to deliver a set of preproteins to the receptor for subsequent membrane translocation dependent on the HSP90 ATPase. Disruption of the chaperone/TOMM70 recognition inhibited the import of these preproteins into mitochondria.
Catalogue number: KTE60159
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O94826
Gene: 9868
Additional info: Human Mitochondrial import receptor subunit TOM70 (TOMM70A) ELISA Kit has high sensitivity and excellent specificity for detection of Human TOMM70A. No significant cross-reactivity or interference between Human TOMM70A and analogues was observed.

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