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Human Mothers against decapentaplegic homolog 5 (SMAD5) ELISA Kit

Cat no: KTE60572

Human Mothers against decapentaplegic homolog 5 (SMAD5) ELISA Kit

SMAD5 or Mothers against decapentaplegic homolog 5 is a polypeptide that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF? superfamily of modulators. Like many other TGF? family members SMAD5 is involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's).\nThe binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase. It may play a role in the pathway where TGF? is an inhibitor of hematopoietic progenitor cells.

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SPECIFICATIONS

Catalog Number

KTE60572

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4090

Accession

Q99717

Additional Info

Human Mothers against decapentaplegic homolog 5 (SMAD5) ELISA Kit has high sensitivity and excellent specificity for detection of Human SMAD5. No significant cross-reactivity or interference between Human SMAD5 and analogues was observed.

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