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Human Mothers against decapentaplegic homolog 5 (SMAD5) ELISA Kit

Cat no: KTE60572


Supplier: Abbkine Scientific Co.Ltd.
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SMAD5 or Mothers against decapentaplegic homolog 5 is a polypeptide that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF? superfamily of modulators. Like many other TGF? family members SMAD5 is involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase. It may play a role in the pathway where TGF? is an inhibitor of hematopoietic progenitor cells.
Catalogue number: KTE60572
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q99717
Gene: 4090
Additional info: Human Mothers against decapentaplegic homolog 5 (SMAD5) ELISA Kit has high sensitivity and excellent specificity for detection of Human SMAD5. No significant cross-reactivity or interference between Human SMAD5 and analogues was observed.

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