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Human Mothers against decapentaplegic homolog 7 (Smad7) ELISA Kit

Human Mothers against decapentaplegic homolog 7 (Smad7) ELISA Kit

Cat no: KTE60571

Supplier: Abbkine Scientific Co.Ltd.
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MAD proteins, originally defined in Drosophila, are essential components of the signaling pathways of the transforming growth factor-beta receptor family. Using a differential display approach in cultured endothelial cells subjected to multiple soluble and biomechanical stimuli, Topper et al. (1997) isolated a human endothelial cell cDNA encoding MADH7, which they called SMAD7. The predicted 426-amino acid MADH7 protein lacks the C-terminal putative phosphorylation sites present in other MAD proteins, suggesting that it may be distinctly regulated. In situ hybridization and immunohistochemical analyses on human tissues showed that MADH7 is expressed predominantly in vascular endothelium.
Catalogue number: KTE60571
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O15105
Gene: 4092
Additional info: Human Mothers against decapentaplegic homolog 7 (Smad7) ELISA Kit has high sensitivity and excellent specificity for detection of Human SMAD7. No significant cross-reactivity or interference between Human SMAD7 and analogues was observed.

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